Bioethicists in healthcare institutions have the skills and insights and can and must facilitate and promote measures that address deeply ingrained structural issues that exacerbate health inequity...

Volume 24, Issue 8, August 2024, Page 43-45.

Filosofische ponering van de subjectiviteit van elke interpretatie.

Three remarks, which are sometimes made about Freud's distiction between Ego and Id are discussed: 1. This distinction would have no analogy in other psychological concepts. 2. The essence of the "I" would be misjudged here. 3. It would be the rest of an atomising psychology, not yet arriving at the modern views of totality. Although the common parlance concerning psychic "parts" has indeed analogies in the old atomistic-psychological conceptions, these instances, as well as the conflicting drives are and have (...) been always considered in psychoanalysis as expressions of which the person himself is the subject. Especially the concept "Id" must be looked at as equivalent to the biological total, to the concept: Person-Stern. The concept I or Ego, as a special structure of "figure" within this whole, means no split-off part, but is equivalent to what is called elsewhere "durchstrukturiertes Unterganze". Freud entitles a certain intern organisation with the word "Ich". He that thinks the essence of "the" I herewith misjudged, confuses word and concept -- the word I contains a lot of equivocations. That there are conflicts within the person is a basic matter of fact, which is not to be pushed aside in favour of totalitarian dogmatics, this conflict must be expressed in our terminology in some way or other. Terms, by way of comparison borrowed from material situations cannot always be avoided, and need not give any inconvenience, provided reflecting over the import of the terms is practised sufficiently. (shrink)

Regulated secretory proteins are stored within specialized vesicles known as secretory granules. It is not known how proteins are sorted into these organelles. Regulated proteins may possess targeting signals which interact with specific sorting receptors in the lumen of the trans‐Golgi network (TGN) prior to their aggregation to form the characteristic dense‐core of the granule. Alternatively, sorting may occur as the result of specific aggregation of regulated proteins in the TGN. Aggregates may be directed to secretory granules by interaction of (...) a targeting signal on the surface with a sorting receptor. Novel targeting signals which confer on regulated proteins a tendency to aggregate under certain conditions, and in so doing cause them to be incorporated into secretory granules, have been implicated. Specific targeting signals may also play a role in directing membrane proteins to secretory granules. (shrink)

In this paper I propose a reading of Plotinus Enneads VI.1-3 [41-43] On the genera of being which regards this treatise as a coherent whole in which Aristotle's "Categories" is explored in a way that turns it into a decisive contribution to Plotinus' Platonic ontology. In addition, I claim that Porphyry's Isagoge and commentaries on the "Categories" start by adopting Plotinus' point of view, including his notion of genus, and proceed by explaining its consequences for a more detailed reading of (...) the "Categories." After Plotinus' integration of the "Categories" into the Platonic frame of thought Porphyry saw the possibilities of exploiting the Peripatetic tradition both as a means to support the Platonic interpretation of the "Categories" and as a source for solutions to traditional questions. His allegiance to a division of being into ten, and his emphasis on semantics rather than ontology can be explained from this orientation. In the light of our investigation the alleged disagreement between Plotinus and Porphyry on the "Categories" changes its appearance completely. There are differences, but these can be best explained as confirmation and extension of Plotinus' perspective on the "Categories" and its role in Platonism. (shrink)